Soft Tissue Sarcoma Trials
Trial Name
Subtype
Agents
Phase
Status
Sponsor
Clear Cell Sarcoma
Tebentafusp vs. Physician’s choice
II
Open, recruiting
Sarcoma Alliance for Research through Collaboration (SARC)
Soft Tissue Sarcoma
GD2-SADA, 177Lu-DOTA
I
Open, recruiting
Y-mAbs Therapeutics
Soft Tissue Sarcoma
[Ac-225] RTX-2358, diagnostic test: [Cu64]LNTH-1363S
I/II
Open, recruiting
Ratio Therapeutics, Inc.
Soft Tissue Sarcoma
Preoperative Radiotherapy
II
Open, recruiting
The Netherlands Cancer Institute
Frontline and Relapsed RhabdoMyoSarcoma
Various agents
III
Open, recruiting
University of Birmingham
Metastatic Leiomyosarcoma (LMS)
Lurbinectedin + doxorubicin
IIb/III
Open, recruiting
PharmaMar
Advanced or metastatic Soft Tissue Sarcoma
Onfekafusp alfa (L19TNF) + Doxorubicin vs. Doxorubicin alone
III
Open, recruiting
Philogen S.p.A.
Soft Tissue Sarcoma
M2554
I
Open, recruiting
EMD Serono Research & Development Institute, Inc.
Synovial sarcoma and myxoid/round cell liposarcoma (MRCLS)
DS-2243a
I
Open, recruiting
Daiichi Sankyo
Advanced solid tumors incl. EHE
IAG933
I
Closed for recruitment, but active
Novartis Pharmaceuticals
Solid tumors incl. soft tissue sarcomas
AVA6000
I
Open, recruiting
Avacta Life Sciences Ltd.
Advanced Pediatric Solid & CNS Tumors
LOXO-292
I/II
Active, not recruiting
Loxo Oncology, Inc. (Eli Lilly)
Liposarcoma, leiomyosarcoma, UPS
INT230-6
III
Active, not recruiting
Intensity Therapeutics, Inc.
Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Gene therapy: ADP-A2M
II
Active, not recruiting
Adaptimmune
Solid tumors incl. soft tissue and bone sarcomas
TNG908
I/II
Closed for recruitment
Tango Therapeutics
Solid tumors incl. soft tissue and bone sarcomas
TNG462
I/II
Open, recruiting
Tango Therapeutics
Extremity Soft Tissue Sarcomas
Preoperative Radiotherapy
II
Open, recruiting
The Netherlands Cancer Center
Advanced or Metastatic Soft-tissue Sarcoma
Dacarbazine + L19TNF
II
Closed for recruitment, but active
Philogen S.p.A.