GIST Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

StrateGIST 3

Advanced GIST

IDRX-42 and Sunitinib

III

Open, recruiting

GlaxoSmithKline

POLARIS-3: A Study of Olverembatinib in SDH-deficient GIST

Advanced GIST

Olverembatinib

III

Open, recruiting

Ascentage

StrateGIST Frontline

Advanced GIST

Velzatinib (IDRX-42) vs. Imatinib

III

Not yet recruiting

GlaxoSmithKline

Peak: CGT9486+Sunitinib vs. Sunitinib in GIST

Advanced GIST

CGT9486 (Bezuclastinib) and Sunitinib

III

Closed for recruitment, but active

Cogent Biosciences, Inc.

INSIGHT: Ripretinib vs. sunitinib

Advanced GIST

Ripretinib vs. Sunitinib

III

Closed for recruitment, but active

Deciphera Pharmaceuticals

SSG XXII: 3 vs. 5 years of adjuvant imatinib

Operable GIST

Imatinib

III

Closed for recruitment, but active

Scandinavian Sarcoma Group (SSG)