Bone Sarcoma Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Conventional chondrosarcoma

INBRX-109 vs. placebo

II

Open, recruiting

Inhibrx, Inc.

Ewing's sarcoma

Different chemotherapy regimens

II/III

Open, recruiting

University of Birmingham

Osteosarcoma

Cabozantinib

II

Open, recruiting

Ipsen

Conventional chondrosarcoma

Ivosidenib vs. placebo

III

Open, recruiting

Servier Bio-Innovation LLC

Ewing Sarcoma / SDH-deficient GIST

INBRX-109

I

Open, recruiting

INHIBRX Inc.

Ewing's sarcoma, Chondrosarcomas, Osteosarcomas, Chondromas

Regorafenib vs. placebo

II

Open, recruiting (France only)

UNICANCER

Ewing Sarcoma in children/young adults

Lurbinectedin

I/II

Open, recruiting

Jazz Pharmaceuticals

Solid tumors incl. soft tissue and bone sarcomas

TNG462

I/II

Open, recruiting

Tango Therapeutics

Ewing's Sarcoma

Abemaciclib (LY2835219) + Irinotecan + Temozolomide

II

Open, recruiting

Eli Lilly and Company

Ewing Sarcoma / Pediatric Patients

Palbociclib in combination with chemotherapy

II

Closed for recruitment, but active

Pfizer

Solid tumors incl. soft tissue and bone sarcomas

TNG908

I/II

Closed for recruitment

Tango Therapeutics

National trial lists

Some of our SPAGN member groups run clinical trial registries to inform about national and international trials in their respective countries.
Browse here to find out more:

Consortia dealing with bone sarcomas

These consortia develop and maintain a strategy to enhance collaboration among clinicians, researchers, and patient advocates across Europe and/or globally. Their goal is to strengthen and align efforts to address the current gaps in knowledge and treatment for specific subtypes of bone sarcomas.