Posts by cowic

Randomized trial of Crenolanib in patients with D842V mutated GIST Trial name CrenoGIST Agents: Crenolanib vs. placebo Phase III Status  Closed, active Sponsor Arog Pharmaceuticals, Inc.   Further information: https://clinicaltrials.gov/ct2/show/NCT02847429?term=crenolanib+Gist&rank=2   WHO is the trial for? Patients with confirmed advanced or metastatic GIST with a D842V mutation in the PDGFRA gene Overall health status of the…

ALT GIST The ALT-GIST compares imatinib with an alternating regime of imatinib and regorafenib in patients with confirmed, metastatic GIST without previous therapy. The trial is currently open for participation in several countries. Agents: Imatinib alternating with Regorafenib vs. Imatinib alone Phase II Status  Closed, active Sponsor The Australasian Gastro-Intestinal Trials Group in collaboration with…

CABO GIST Agents: Cabozantinib Phase II Status  Completed Sponsor EORTC   Further information: https://clinicaltrials.gov/ct/show/NCT02216578 or http://www.eortc.org/research_field/clinical-detail/1317/   WHO is the trial for? Patients with metastatic GIST (histologically confirmed) and removed primary tumor Patients with progression during treatment of GIST (before or after surgery, with or without metastasis) with imatinib and sunitinib (but no further/other therapies) Overall…

The Mitigate Project Agents: A novel PET-CT tracer specifically developed to target cell surface receptors of GIST cells Phase I/IIa Status  Open, recruiting Sponsor Medical University Innsbruck, European Union Further information: www.mitigate-project.eu WHO is the trial for?   Patients with progressive disease who have at least been treated with imatinib are eligible The study addresses…

Surgery With or Without Radiation Therapy in Treating Patients With Previously Untreated Nonmetastatic Retroperitoneal Soft Tissue Sarcoma (STRASS) Agents: Radiation therapy followed by surgery vs. surgery alone Phase III Status  Open, recruiting Sponsor European Organisation for Research and Treatment of Cancer – EORTC Further information    Link zu Details (to be inserted) WHO is the trial…

SPAEN Advocacy in Action Award 2021 announced for best projects in sarcoma patients advocacy Patient advocacy ensures that people are heard, take action and ultimately improve situations, achieve changes or help to fulfil unmet medical needs. We believe it is time to shout out about how important patient advocacy in sarcomas is – for patients,…

  Patient advocacy ensures that people are heard, take action and ultimately improve situations, achieve changes or help to fulfil unmet medical needs. The projects that were entered for the “Sarcoma Advocacy in Action Award 2018” once again showed this impressively! All entries were fantastic and the jury had a hard job to decide on…

by Roger Wilson, co-founder and honorary president of SPAEN and founder of Sarcoma UKResearch Involvement and Engagement, February 2018   Patient involvement in research is about adding value rather than commenting on technical quality. After 15 yearsas an involved patient in cancer research I started looking around and I found I was asking myself, where…