Blog & News
ANITA
ANITA – Nintedanib with Ifosfamide in advanced, metastatic Soft Tissue Sarcoma (STS) Agents: Nintedanib vs. Ifosfamide Phase II Status Closed, active Sponsor EORTC in collaboration with Boehringer Ingelheim Further information: https://clinicaltrials.gov/ct/show/NCT02808247 or http://www.eortc.org/research_field/clinical-detail/1506/ A Phase II study comparing Nintedanib…
Navigator: Avapritinib (BLU-285)
NAVIGATOR: Avapritinib (BLU-285) Phase I study of Avapritinib (formerly BLU-285) in patients with GIST and other relapsed/refractory solid tumors (Navigator). Trial name: Navigator Agents: Avapritinib (formerly BLU-285) Phase I Status Completed Sponsor Blueprint Medicines Corporation Further information: https://www.clinicaltrials.gov/ct2/show/NCT02508532?term=NCT02508532&rank=1 WHO is the trial…
Cabozantinib in High Grade Uterine Sarcoma (HGUtS)
Maintenance therapy with Cabozantinib in High Grade Uterine Sarcoma (HGUtS) Agents: Cabozantinib Phase II Status Open, recruiting Sponsor EORTC Further information: https://clinicaltrials.gov/ct/show/NCT01979393 or http://www.eortc.org/research_field/clinical-detail/62113/ A phase II study evaluating the role of maintenance therapy with Cabozantinib in High Grade Uterine…
Crenolanib in patients with D842V mutated GIST
Randomized trial of Crenolanib in patients with D842V mutated GIST Trial name CrenoGIST Agents: Crenolanib vs. placebo Phase III Status Closed, active Sponsor Arog Pharmaceuticals, Inc. Further information: https://clinicaltrials.gov/ct2/show/NCT02847429?term=crenolanib+Gist&rank=2 WHO is the trial for? Patients with confirmed advanced or metastatic GIST…
Euro Ewing 2012
Trial for the Treatment of Newly Diagnosed Ewing’s Sarcoma Family of Tumours Agents: Different chemotherapy regimens Phase III Status Open, recruiting Sponsor University of Birmingham Further information: https://www.ucl.ac.uk/cancer/research/centres-and-networks/euro-ewing-consortium/clinical-trials/euro-ewing-2012/ee2012 WHO is the trial for? Patients with diagnosed Ewing’s sarcoma, primitive…
ALT GIST
ALT GIST The ALT-GIST compares imatinib with an alternating regime of imatinib and regorafenib in patients with confirmed, metastatic GIST without previous therapy. The trial is currently open for participation in several countries. Agents: Imatinib alternating with Regorafenib vs. Imatinib alone Phase…
CABO GIST
CABO GIST Agents: Cabozantinib Phase II Status Completed Sponsor EORTC Further information: https://clinicaltrials.gov/ct/show/NCT02216578 or http://www.eortc.org/research_field/clinical-detail/1317/ WHO is the trial for? Patients with metastatic GIST (histologically confirmed) and removed primary tumor Patients with progression during treatment of GIST (before or after surgery,…
Mitigate
The Mitigate Project Agents: A novel PET-CT tracer specifically developed to target cell surface receptors of GIST cells Phase I/IIa Status Open, recruiting Sponsor Medical University Innsbruck, European Union Further information: www.mitigate-project.eu WHO is the trial for? Patients with progressive disease…
STRASS Trial
Surgery With or Without Radiation Therapy in Treating Patients With Previously Untreated Nonmetastatic Retroperitoneal Soft Tissue Sarcoma (STRASS) Agents: Radiation therapy followed by surgery vs. surgery alone Phase III Status Open, recruiting Sponsor European Organisation for Research and Treatment of Cancer –…
SPAEN Advocacy in Action Award 2021
SPAEN Advocacy in Action Award 2021 announced for best projects in sarcoma patients advocacy Patient advocacy ensures that people are heard, take action and ultimately improve situations, achieve changes or help to fulfil unmet medical needs. We believe it is time to…