Study Registry
Taking part in a clinical trial can be a good choice but it is often hard to find a clinical trial that is right for you. Many patient organizations and websites maintain lists of clinical trials. The following table lists some of the clinical trials available worldwide. Please note: this is not an exhaustive list, so please check with your local patient organization. Other trials may be available in your country. If you are aware of an open trial that should be listed here, please send us the trial information to: info@sarcoma-patients.org
Soft Tissue Sarcoma Trials
Trial Name
Subtype
Agents
Phase
Status
Sponsor
Advanced/ metastatic solid tumors incl. sarcomas
Milademetan
II
Open, recruiting
Rain Oncology
Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Gene therapy: ADP-A2M
II
Open, recruiting
Adaptimmune
Solid tumors incl. malignant peripheral nerve sheath tumor (MPNST)
TNG908
I/II
Open, recruiting
Tango Therapeutics
Epithelioid Sarcoma
Tazemetostat + doxurubicin vs. docurubicin + placebo
III
Open, recruiting
Epizyme Inc.
Extremity Soft Tissue Sarcomas
Preoperative Radiotherapy
II
Open, recruiting
The Netherlands Cancer Center
Bone Sarcoma Trials
Trial Name
Subtype
Agents
Phase
Status
Sponsor
Ewing's sarcoma
Different chemotherapy regimens
II/III
Open, recruiting
University of Birmingham
Ewing Sarcoma / Pediatric Patients
Palbociclib in combination with chemotherapy
II
Open, recruiting
Pfizer
Ewing's sarcoma, Chondrosarcomas, Osteosarcomas, Chondromas
Regorafenib vs. placebo
II
Open, recruiting (France only)
UNICANCER
GIST Trials
Trial Name
Subtype
Agents
Phase
Status
Sponsor
Operable GIST
Imatinib
III
Open, recruiting
Scandinavian Sarcoma Group (SSG)
Desmoid / TGCT Trials
Progressing Desmoid Tumors
AL 102 vs. placebo
II/III
Open, recruiting
Ayala Pharmaceuticals, Inc.
Desmoid Tumor/Aggressive Fibromatosis
Nirogacestat
III
Closed, but active
SpringWorks Therapeutics, Inc.
Tenosynovial Giant Cell Tumor (TGCT)
Vimseltinib
III
Open, recruiting
Deciphera Pharmaceuticals LLC
Chordoma trials
The Chordoma Foundation has a extensive list of clinical trials designed specifically for chordoma patients, as well as other relevant trials recommended by the Chordoma Foundation’s MAB on their website. Please see for the clinical trials list here
Expanded access programms
An Expanded Access Program (EAP) allows physicians and patients access to pre-approval, investigational drugs outside of the clinical trial setting. An EAP can also be called a Managed Access Program (MAP), Early Access Program, or Compassionate Use Program (CUP).
- Blueprint Medicines has a pre-approval access programme for avapritinib and pralsetinib.
Please see further information here: https://www.blueprintmedicines.com/pipeline/pre-approval-access-policy/ - Deciphera has established an EAP for ripretinib.
Please see further information here: https://www.deciphera.com/pipeline/expanded-access/