Study Registry

Taking part in a clinical trial can be a good choice but it is often hard to find a clinical trial that is right for you. Many patient organizations and websites maintain lists of clinical trials. The following table lists some of the clinical trials available worldwide. Please note: this is not an exhaustive list, so please check with your local patient organization. Other trials may be available in your country. If you are aware of an open trial that should be listed here, please send us the trial information to: info@sarcoma-patients.org

Soft Tissue Sarcoma Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Liposarcoma

BI 907828

III

Open, recruiting

Boehringer Ingelheim

Leiomyosarcoma

Unesbulin

II/III

Open, recruiting

PTC Therapeutics

Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Gene therapy: ADP-A2M

II

Open, recruiting

Adaptimmune

Leiomyosarcoma & Liposarcoma

Preoperative chemotherapy & surgery

III

Open, recruiting

EORTC

Epithelioid Sarcoma

Tazemetostat + doxurubicin vs. docurubicin + placebo

III

Open, recruiting

Epizyme Inc.

Extremity Soft Tissue Sarcomas

Preoperative Radiotherapy

II

Open, recruiting

The Netherlands Cancer Center

Bone Sarcoma Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Ewing's sarcoma

Different chemotherapy regimens

II/III

Open, recruiting

University of Birmingham

Ewing Sarcoma / Pediatric Patients

Palbociclib in combination with chemotherapy

II

Open, recruiting

Pfizer

Ewing's sarcoma, Chondrosarcomas, Osteosarcomas, Chondromas

Regorafenib vs. placebo

II

Open, recruiting (France only)

UNICANCER

GIST Trials

Trial Name

Subtype

Agents

Phase

Status

Sponsor

Advanced GIST

IDRX-42

I

Open, recruiting

IDRx Inc

Operable GIST

Imatinib

III

Open, recruiting

Scandinavian Sarcoma Group (SSG)

KIT/PDGFR wild type GIST

Regorafenib

II

Open, recruiting

Grupo Espanol de Investigacion en Sarcomas

Desmoid / TGCT Trials

Progressing Desmoid Tumors

AL 102 vs. placebo

II/III

Open, recruiting

Ayala Pharmaceuticals, Inc.

Desmoid Tumor/Aggressive Fibromatosis

Nirogacestat

III

Closed, but active

SpringWorks Therapeutics, Inc.

Tenosynovial Giant Cell Tumor (TGCT)

Vimseltinib

III

Open, recruiting

Deciphera Pharmaceuticals LLC

The Desmoid Tumour Research Foundation has a extensive list of further ongoing, mostly mono-country clinical trials for patients with desmoid tumour / aggressive fibromatosis. Please find it here.

Chordoma trials

The Chordoma Foundation has a extensive list of clinical trials designed specifically for chordoma patients, as well as other relevant trials recommended by the Chordoma Foundation’s MAB on their website. Please see for the clinical trials list here

Expanded access programms

An Expanded Access Program (EAP) allows physicians and patients access to pre-approval, investigational drugs outside of the clinical trial setting. An EAP can also be called a Managed Access Program (MAP), Early Access Program, or Compassionate Use Program (CUP).