Desmoids
Desmoid Research
For desmoids tumors we have no published phase III randomized clinical trials. Most published data are from retrospective case series. More clinical trials are urgently needed.
Read MoreTreatment of Desmoids
As treatment option should be considered hormonal therapy surgery medical therapy radiotherapy chemotherapy isolated limb perfusion hyperthermia “watch and wait” When a DT is suspected the patient management (including biopsy) in a reference center/network is highly recommended. All subjects should be discussed in a multidisciplinary tumor conference. Furthermore a discussion with the patient is necessary…
Read MoreDiagnosis
A biopsy confirming DT diagnosis is mandatory and a definitive histology should be awaited before undertaking any further treatment steps. Additionally a PET, MRI or CT (abdomen) is the main imaging modality to characterize the disease.
Read MoreSigns and Symptoms
Patients often notice a hard, new or growing lump or swelling associated with pain. Sometimes patients feel a numbness/deafness or prickle or observe a restriction in the mobility/flexibility of the extremities (legs, arms). Desmoids in the abdomen are often diagnosed very late with the consequence of a long unrestricted growth of the tumor. Typical signs…
Read MoreFollow up Desmoid
A close meshed follow up is recommended for critical anatomic sites or in the case of fast growth and growth at several sites (multifocal growing). The timeframe for follow up by MRI/ CT should be made individualized by a multidisciplinary team.
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