Desmoid / TGCT Trials
Desmoid Tumor/Aggressive Fibromatosis (DT/AF)
Nirogacestat (Ogsiveo)
IV
Open, recruiting
SpringWorks Therapeutics
Solid Tumors incl. desmoid tumors/aggressive fibromatosis
FOG-001
I/II
Open, recruiting
Parabilis Medicines, Inc.
Tenosynovial Giant Cell Tumor
Emactuzumab
III
Closed for recruitment, but active
SynOx Therapeutics
Progressing Desmoid Tumors
AL 102 vs. placebo
II/III
Closed for recruitment, but active
Ayala Pharmaceuticals, Inc.
Tenosynovial Giant Cell Tumor
Pimicotinib (ABSK021)
III
Closed for recruitment, but active
Abbisko Therapeutics Co, Ltd
Tenosynovial Giant Cell Tumor (TGCT)
Vimseltinib
III
Closed for recruitment, but active
Deciphera Pharmaceuticals LLC
The Desmoid Tumour Research Foundation has a extensive list of further ongoing, mostly mono-country clinical trials for patients with desmoid tumour/aggressive fibromatosis. Please find it here.