New Horizons GIST 2020
Special Topic: Mutational Analysis in GIST as a guide for the right therapy - May 7, 2021
For several years now NEW HORIZONS GIST is the most important global platform for GIST patient advocates with a focus on discussing critical information about GIST that impacts the global GIST patient and medical communities. Due to the current coronavirus pandemic, the 2020 New Horizons GIST conference was held as a virtual conference in September 2020 (see a report about the meeting and its very interesting sessions here (pdf download) as well as all available ressources including presentations and recordings here).
In an extra 2 hours online meeting at 7th of May we focused on
"Mutational Analysis in GIST as a guide for the right therapy" as a special topic.
The programme included the following talks:
|Introduction to the topic of Mutational Analysis
>> See slides (pdf download)
Markus Wartenberg, SPAEN
|Key Notes Mutations and Mutational Analysis in GIST|
|GIST-Pathologist: Dr. Andrew Rosenberg, USA
- What is the role of a pathologist in the interdisciplinary GIST team?- How do GISTs arise genetically / biologically?- What types of mutations are there in GIST?- Closer look on mutations in KIT/PDGFRA?- What is the difference between primary and secondary mutations?- Does the mutation have an impact on the course of the disease / prognosis?GIST-Pathologist: Eva Wardelmann, GER
- In simple steps: How does such a mutational analysis work?
- Costs, time and efforts of mutational analysis?
- What role does/can liquid biopsy play in GIST?
- What do we know about rare mutations -
- What are the three most burning (scientific) questions
|Key Notes Impact of mutations in clinical practice|
|GIST-Expert/-Oncologist: Rashmi Chugh, USA
>> See slides (pdf download)
The influence of the mutation result on the choice of therapy- In which cases do primary mutations guide the choice of therapy?- What role do secondary mutations play in therapy decision?- What about treatment option for specific, very rare mutations,
such as BRAF, SDH- or NTRK?GIST-Expert/-Oncologist: Peter Reichardt, GER
Patient cases with rare mutations in which the quality
of therapy management has made a clear difference?
|Country Presentations on experiences with mutational analysis||Recording|
The corona virus has dramatically changed our private lives and our lives as Patient Advocates worldwide. So, also NEW HORIZONS GIST 2020 was held virtually!
As many of you have already experienced: NEW HORIZONS GIST is a great opportunity where “GIST Patient Advocates / GIST Patient Group Leaders” from around the world are coming together - this time virtually!
If you have any questions, please e-mail to email@example.com
>> Slidedecks of the presentations for download
|GIST Episode 1: Introduction – Overview
Speaker: Hans Gelderblom, NL
|GIST Episode 2: Biology – Genetics – Pathology
Speaker: David Josephy, CDN
|GIST Episode 3: Localized, operable primary tumor
Speaker: Peter Reichardt, DE
|GIST Episode 4: Metastatic (advanced) disease
Speaker: Albiruni Razak, CDN
|GIST Episode 5: Progression of metastatic disease under drug treatment
Speaker: Breelyn Wilky, US
|GIST Episode 6: Introducing new treatment options in GIST
Speaker: Jon Trent, US
|GIST Episode 7: Challenges in approaching a non-KIT/PDGFR mutated GIST
Speaker: Ramesh Bulusu & Ruth Casey, UK
|GIST Episode 8: Following the research journey in GIST
Speaker: Robin Jones, UK
|GIST Episode 9: Quality of diagnosis, treatment & care
Speaker: Gina D'Amato, US
>> Video recordings of the presentations
Find more videos on our Youtube Channel!
Previous New Horizons GIST Meetings
For several years now, NEW HORIZONS GIST is the most important global annual conference for GIST patient advocates. At NEW HORIZONS GIST, patients from the global GIST patient community come together, can interact with top GIST experts, have access to state‐of‐the‐art medical and scientific information and can exchange best practice in patient advocacy among each other. The conference is a balanced symbiosis of medical content, advocacy topics and capacity building sessions. It is held every year and organised by either American Groups (The Life Raft Group/Alianza GIST) or European Groups in cooperation with SPAEN.
NEW HORIZONS GIST 2020 was held virtually due to COVID-19. Please see all relevant information here.
NEW HORIZONS GIST 2018 was held in Vienna, Austria, in September 2018
NEW HORIZONS GIST 2017 was held in Wayne, New Jersey, USA from October 1-3, 2017.
NEW HORIZONS GIST 2016 was held in Sitges/Barcelona, Spain from May 18-21, 2016.