Editorial Guidelines for SPAGN Blog

1. The Blog’s Mission / Slogan The purpose of the SPAGN Blog is to cover topics of interest to the wider SPAGN community, with the aim of conveying information, sharing experiences and viewpoints, and strengthening the bonds of the SPAGN community. Slogans: “Strengthening the international sarcoma community by sharing knowledge and experience” and “Building a…

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Commenting Policy

We encourage you to share your thoughts as they relate to topics being discussed in the Voices of Sarcoma blog. We review and post comments according to the policy below. We reserve the right to not post comments or to remove comments that are inconsistent with our policy. Comments that include the following will not…

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What are your priorities in bone sarcoma research?

Research Priorities in Bone Sarcomas Bone sarcomas are a diverse and hard to treat group of rare cancers. People with bone sarcomas (or primary bone cancer) have high unmet medical needs, and face a range of challenges including delays to diagnosis, disparities in access to treatments and a relative lack of clinical trial and research opportunities.…

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Treament News in GIST: EU – Approval for Ripretinib in forth-line

Good news for GIST patients in the EU: In November 2021, the EMA has granted marketing approval for ripretinib (Qinlock®) for patients with advanced gastrointestinal stromal tumours (GIST) who already received three or more kinase inhibitors prior. Read EMA’s press release here: https://www.ema.europa.eu/en/medicines/human/summaries-opinion/qinlock

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New Study on Preoperative Radiotherapy in Extremity Sarcomas

Currently, soft tissue sarcomas (STS) are preoperatively irradiated in a conventionally fractionated regimen of 25 x 2 Gy in five weeks. Recent radiobiological investigations, however, have revealed a rationale for sensitivity to (modest) hypofractionation. The so called “SCOPES” study (Short Course Of Preoperative radiotherapy in Extremity Sarcomas) will investigate, in a prospective randomized trial, a…

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Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients

As leiomyosarcoma patients are challenged by the development of metastatic disease, effective systemic therapies are the cornerstone of outcome. However, the overall activity of the currently available conventional systemic treatments and the prognosis of patients with advanced or metastatic disease are still poor, making the treatment of this patient group challenging. Therefore, in a joint…

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E-Learning: Diagnosis and Management of Bone Sarcoma

Diagnosis and Management of Bone Sarcomaby Dr. Silvia Stacchiotti, Italy & Prof. Florence Duffaud, France This accredited e-learning by Sarcoma Connect provides an overview of Bone Sarcoma, covers the unique characteristics of a range of sub-types, the multi-disciplinary specialists who should be involved and at what stage, and the patient journey beyond referral. The course…

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New ESMO Guidelines for GIST, Bone Sarcomas and Soft Tissue Sarcomas

  The updated ESMO-EURACAN-GENTURIS (European Society for Medical Oncology; European Reference Network for Rare Adult Solid Cancers; European Reference Network for Genetic Tumour Risk Syndromes) Clinical Practice Guidelines for Gastrointestinal Stromal Tumours have been published in Annals of Oncology at September 2021, following an update of the guidelines for Bone Sarcomas and Soft Tissue Sarcomas…

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