Strass Trial



is the trial for?

•    Patients with histologically confirmed retroperitoneal sarcoma (RPS)
•    No metastasis
•    Previously untreated
•    Tumor must be operable, suitable for radiotherapy and radiologically measurable (RECIST 1.1)
•    Overall health status of the patient has to be good (WHO performance status 0-2)
•    No other malignant tumor disease within the past 5 years


is the key question that this
trial is attempting to answer?

Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. It is not yet known whether surgery is more effective with or without radiation therapy in treating nonmetastatic retroperitoneal soft tissue sarcoma.

This randomized phase III trial is studying radiation therapy followed by surgery to see how well it works compared with surgery alone in treating patients with previously untreated nonmetastatic retroperitoneal soft tissue sarcoma.


patients might want to participate?

This clinical trial offers patients an opportunity to access a new therapy strategy. This trial will further support the research in retroperitoneal soft-tissue sarcoma and potentially help other patients with this disease. The trial might or might not have benefit in your individual case. For more about the importance and benefits of joining clinical trials, please click here.


will the trial be open?

The study is open (recruiting) – 256 patients are expected to participate.


is the trial available?

The trial was available in 34 study centers in several countries in Europe, the USA and Canada    
For a complete list of trial locations, please see here
Study coordinator:
Contact: Anne Kirkpatrick
Phone: +32 27741691


What does the study look like?

There will be 2 study arms (groups): all participating patients will be randomly divided (by a computer) in two groups. Patients in one group will be assigned to radiotherapy followed by surgery. Patients in the other group will receive surgery alone.


do I get more information?

Patient organisations supporting sarcoma patients in your country may offer additional information about the trial, current recruitment status, and key contacts. Click here for a list of patient organisations serving sarcoma patients. If there are no such organisations in your country, please email us for more information: Send e-mail


with other patients on this trial

If you want to connect with other patients considering or participating in this trial, you can find them here: List of organisations worldwide.


your experience

You want to share your experience on this trial?
Send us an e-mail to:
Note that your experience would be helpful for other patients and patient organisations.


of the study

No results are available at this time. Future results will be linked here.


Disclaimer: This is a patient-friendly summary of the clinical trial which has been provided for informational purposes only. Patients should consult their physician about any clinical trial opportunity.

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